VALLERIOLE (François). Observationum Medicinalium lib. vj. Denuo editi, & emendatiores quàm antea in lucem emissi. Lyon: Antoine Blanc (Antonium Candidum), 1588. - In-8, soft vellum overlapping, smooth spine (contemporary binding). Very rare second edition, published posthumously, dedicated to the Italian Cardinal Prospero Santa Croce (1513?-1589). This work was first published in 1573. Composed by the physician and professor of medicine François Valleriole (1504-1580), it offers, in 6 books, 60 sometimes astonishing medical observations. Among these observations are the story of a paralytic healed by the fear of being burned in a fire, the story of the appearance in 1553 in Arles of thousands of locusts and the means used to destroy them, the names of the main patients in Arles cured by the author, etc. Good copy in contemporary binding. The guards are loaded with old notes, and notes also appear in a few margins. Copy of the poet and academician Victor de Laprade (1812-1883). The leather bindings are missing. Tears in the first guard. Wet spots. Provenance: Victor de Laprade, with ex-libris.